component of Prophyllin
Propionic acid, sodium salt
CAS: 137-40-6
Molecular Formula: C3H6O2.Na
component of Prophyllin - Names and Identifiers
| Name | Propionic acid, sodium salt |
| Synonyms | Spac deketon Impedex bioban-s propisol whit-pro propanoate sodiumpropanoate Sodium propionate sodium propanoate calcium dipropanoate component of Prophyllin Propionic acid, sodium salt Propanoic acid, sodium salt propionic acid sodium type I propionic acid sodium insect cell*culture tested |
| CAS | 137-40-6 |
| EINECS | 205-290-4 |
| InChI | InChI:1S/C3H6O2.Na/c1-2-3(4)5;/h2H2,1H3,(H,4,5);/q;+1/p-1 |
component of Prophyllin - Physico-chemical Properties
| Molecular Formula | C3H6O2.Na |
| Molar Mass | 96.06 |
| Density | 1.51[at 20℃] |
| Melting Point | 285-286 °C (lit.) |
| Boling Point | 141.7°C at 760 mmHg |
| Flash Point | 57.7°C |
| Water Solubility | 995 g/L (20 ºC) |
| Solubility | At 25 ℃, 1g is dissolved in about 1ml of water, about 0-65ml of boiling water and about 24ml of ethanol at 25 ℃. |
| Vapor Presure | 0Pa at 20℃ |
| Appearance | Colorless crystal |
| Color | White |
| Merck | 14,8669 |
| BRN | 3566934 |
| PH | 8-9.5 (10g/l, H2O, 20℃) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Stability | Stable. Incompatible with strong oxidizing agents. Hygroscopic. |
| Sensitive | Hygroscopic |
| MDL | MFCD00002759 |
| Physical and Chemical Properties | transparent particles or crystal, there is a specific odor. Deliquescence in moist air. |
| Use | Used as a preservative, used for cakes, waxberry and other Mold |
component of Prophyllin - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R21 - Harmful in contact with skin R38 - Irritating to the skin R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S36/37 - Wear suitable protective clothing and gloves. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
| WGK Germany | 1 |
| RTECS | UF7525000 |
| FLUKA BRAND F CODES | 3 |
| TSCA | Yes |
| HS Code | 29159000 |
component of Prophyllin - Upstream Downstream Industry
| Raw Materials | Propionic acid Sodium carbonate Sodium hydroxide |
component of Prophyllin - Reference
| Reference Show more | 1. [IF=4.677] Xu Xiaohan et al."Gut Microbial Metabolite Short-Chain Fatt Acids Partially Reverse Surgery and Anesthesia-Induced Behavior Deficits in C57BL/6J Mice."Front Neurosci-Switz. 2021 Jun;0:593 2. [IF=4.952] Aiyu Qu et al."Investigation of gas-producing bacteria in sufu and its effective method to control their growth."Lwt Food Sci Technol. 2022 Feb;155:112919 |
component of Prophyllin - Nature
Open Data Verified Data
transparent particles crystallized in moist air. Soluble in water, slightly soluble in alcohol. At 25 °c, 1g of the product was dissolved in 1ml of water, 0.65mL of boiling water and 24ml of ethanol. It is neutral or weak alkaline to litmus.
Last Update：2024-01-02 23:10:35
component of Prophyllin - Preparation Method
Open Data Verified Data
dissolve sodium carbonate in hot water, slowly add propionic acid at 70 ℃, then heat to boiling, control pH at 6.8~7.3, decolorize, filter, concentrate under reduced pressure, cool, filter, drying is the finished product.
Last Update：2022-01-01 09:30:43
component of Prophyllin - Introduction
The deliquescence in the wet air, with a peculiar odor. It is neutral or weakly alkaline to litmus. It's irritating.
Last Update：2022-10-16 17:13:40
component of Prophyllin - Use
Open Data Verified Data
in leather making, as a masking agent to improve the Alkali resistance of leather and tanning uniformity.
Last Update：2022-01-01 09:30:44
component of Prophyllin - Reference Information
| LogP | -3.23 at 25℃ |
| NIST chemical information | Information provided by: webbook.nist.gov (external link) |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| properties | colorless transparent crystals, particles or white crystalline powder. Odorless or slightly propionic acid-smelling. Easy to deliquesce, easily soluble in water, soluble in ethanol, slightly soluble in acetone. |
| food preservative | sodium propionate is a kind of food preservative and antifungal allowed by GB2760-1996 regulations in our country, which is used for cakes and cheese. It can be used alone or in combination with propionic acid and sorbic acid. It can also be used as a viscous substance inhibitor for beer and the like. Feed additive, etc. The appearance is colorless transparent crystalline or granular crystalline powder, odorless or slightly acetic acid-propionic acid-butyric acid odor. Stable to light and heat, easy to deliquesce in humid air. It is easily soluble in water (100 at 15 ℃ and 150 at 100 ℃), soluble in ethanol (4.4 at 15 ℃ and 8.4 at 100 ℃), slightly soluble in acetone (0.05 at 15 ℃), and is the most active under acidic conditions. It produces free propionic acid, has antibacterial effect, has extensive antibacterial effect on mold, yeast and bacteria, and is ineffective on yeast. Its antibacterial properties are the same as those of propionic acid. Can be used for pastries, bean products, dumpling wrappers, wonton wrappers, raw cut noodles, cheese and other antiseptic mildew. In the processing technology of canned bayberry, it is used to soak bayberry. Used in beer production can inhibit the production of unfavorable sticky substances. Usage and dosage: the recommended dosage is 0~2.5 g/kg. According to the "Hygienic Standard for the Use of Food Additives" (GB 2760-1996), it can be used for cakes with a maximum usage of 2.5 g/kg; Wet products of raw flour (raw cut flour and wonton skin, with a maximum usage of 0.25 g/kg (calculated by propionic acid); Soaked bayberry, the maximum usage is 30~50 g/kg (calculated by propionic acid). Generally, 3% ~ 5% sodium propionate solution is used to soak bayberry. After soaking, it needs to be washed before it can be used to process canned bayberry. Sodium propionate is almost non-toxic to the human body. Mouse oral LD505100mg/kg. ADI is not restrictive. Quality standard: HG 2922-1999 replaces GB 7656-1987. Content (on a dry basis) 99.0% ~ 100.5%; Loss on drying ≤ 1.0%; Iron ≤ 0.003%; Arsenic ≤ 0.0003%; Heavy metal ≤ 0.001%; Alkalinity (calculated as sodium carbonate): passed the test. Industrially produced sodium propionate is obtained by neutralizing propionic acid solution with sodium hydroxide or sodium carbonate. It can also be used to treat skin mycosis, measure transaminase, etc. |
| application | as leavening agent, dough regulator, buffer, tissue modifier, curing agent, nutritional supplement, chelating agent, etc. in the food industry. For example, it is used as a leavening agent for baked products and cakes; bread, biscuit, buffer, pectin curing agent (gel effect); tissue improver for yeast food and meat products, etc. Sodium propionate is used as a food preservative and antifungal agent, and can be used alone or in combination with propionic acid and sorbic acid. Because it is alkaline, it is more suitable for pastry making than calcium propionate. Propionate is of great significance to the preservation of bread, cakes, biscuits and other baked goods. This is because the ionization constant of propionic acid is small, so it still has a good effect under alkaline conditions. It can be used for brewing, which can increase the saccharification power and improve the fermentation ability of beer. It is used as a viscous substance printing preparation or feed additive. |
| scope of use | propionic acid is the product of oxidation of amino acids and fatty acids in human body, so propionic acid and its salts are preservatives with good safety. ADI (permissible daily human intake per kilogram) is not restricted. |
| principle of action | has good efficacy in preventing mold, but has little inhibitory effect on bacteria. for example, bacilli such as bacilli, octobacillus and proteus can only delay their development for 5 days and have no effect on yeast. Sodium propionate is an acid-type preservative, which is mainly undissociated propionic acid, so it should be used in the acidic range. If used for bread fermentation, it can inhibit the growth of miscellaneous bacteria and prevent mildew of cheese products. |
| content analysis | weigh 3g (correct to mg) of the sample after 105 ~ c: drying for 1h, put it into a distillation flask, and add 200ml of 50% phosphoric acid. Boil for 2h and collect distillate. Water is added through a dropping funnel during the distillation process to maintain a volume of about 200ml in the bottle. Phenolphthalein test solution (TS-167) was added as indicator, and the distillate was titrated with 1mol/L sodium hydroxide. Na()H is equivalent to 96.06mg of sodium propionate per mL1mol/L. |
| toxicity | ADI is not restricted (FAO/WHO,2001). LD50 5.1 g/kg (mouse, oral). GRAS(FDA,§ 184.1784,2000). |
| usage limit | GB 2760-96(g/kg): pastry 2.5; Soak bayberry 30-50, impregnate with 3%-5% aqueous solution, and wash before processing, calculated as propionic acid. FAO/WHO(1984): processed cheese 3000 mg/kg. EEC regulations can be used for dairy products, baked products, cheese, etc. It is still used as a viscous substance inhibitor for beer, etc. |
| use | used as a preservative, used for pastries, bayberry and other mildew prevention used as a fungicide, mildew prevention agent preservative; mildew prevention agent. sodium propionate liquid wet acid preservative, its antibacterial effect is affected by environmental PH. The minimum inhibitory concentration was 0.01% at PH5.0 and 0.5% at PH6.5. In acidic medium, it has a strong inhibitory effect on various molds, aerobic bacillus or gram-negative bacilli. It has a special effect on preventing the production of aflatoxin, but it is almost ineffective for yeast. In addition, it is also used as a food preservative. It is used as a binding agent in leather making to improve the alkali resistance of leather and the uniformity of tanning. sodium propionate is also an acid food preservative, and its antibacterial effect is affected by environmental pH value. The minimum inhibitory concentration is 0.01% when the pH value is 5.0 and 0.5% when the pH value is 6.5. It has a strong inhibitory effect on various molds, gram-negative bacilli or aerobic bacilli in acidic media. It has a special effect on preventing the production of aflatoxin, but it is almost ineffective for yeast. In the food industry, it can be used for the preservation of cakes with an amount of 2.5 g/kg (calculated as propionic acid, the same below); The maximum amount of 50 g/kg is soaked in 3% ~ 5% aqueous solution. It can also be used as an antifungal agent for feed. Fungicides, antifungal agents. Determination of transaminase. Food, feed and anti-corrosion and anti-mold agents. The general addition amount is 0.1-0.3%. |
| production method | sodium carbonate powder is dissolved in a neutralization pot, then propionic acid is added to neutralize until pH = 7-8, neutralization temperature is 70-100 ℃, and neutralization time is 2-3h. The neutralization liquid is filtered to remove the insoluble matter, and the clear liquid is concentrated, cooled, crystallized, separated and dried to obtain the finished product. CH3CH2COOH[Na2CO3]→ CH3CH2COONa propionic acid and sodium carbonate react at 80-90 ℃ for 2-3 hours at pH = 7-8. after the reaction, the finished product is obtained by filtration and spray drying. dissolve sodium carbonate in hot water, slowly add propionic acid at 70 ℃, then heat to boiling, pH value should be 6.8~7.3, decolorization, filtration, decompression concentration, cooling, filtration and drying are finished products. Made by neutralization of propionic acid and sodium hydroxide or sodium carbonate. Sodium carbonate powder is dissolved in a neutralization pot, then propionic acid is added to neutralize until PH = 7-8, the neutralization temperature is 70-100 ℃, and the neutralization time is 2-3h. The neutralization liquid is filtered to remove insoluble matter, and the finished product is obtained by concentration, cooling, crystallization, separation and drying at night. It is obtained by neutralizing propionic acid solution with sodium hydroxide or sodium carbonate. |
| category | toxic substances |
| toxicity classification | low toxicity |
| acute toxicity | oral-mouse LD50: 6332 mg/kg |
| flammability hazard characteristics | combustible, the fire field discharges spicy and irritating smoke containing sodium oxide |
| storage and transportation characteristics | warehouse low temperature, ventilation, drying |
| fire extinguishing agent | water, carbon dioxide, dry powder, sand |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-09 19:05:10
Supplier List
Featured ProductsSpot supply
Product Name: SODIUM PROPIONATE Request for quotationCAS: 137-40-6
Tel: +86-518-85110306
Email: sales0257@jskolod.com
Mobile: +86-18805130257
QQ: 3287434604
Wechat: +86-18805130257
WhatsApp: +86-18805130257
Spot supply
Product Name: Propionic acid, sodium salt Request for quotationCAS: 137-40-6
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: Propionic acid, sodium salt Request for quotationCAS: 137-40-6
Tel: +86-17505207175
Email: r@reformchem.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Spot supply
Product Name: Propionic acid, sodium salt Request for quotationCAS: 137-40-6
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Wechat: chemical6666
Multiple SpecificationsSpot supply
Product Name: Sodium propionate Visit Supplier Webpage Request for quotationCAS: 137-40-6
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Sodium Propionate Visit Supplier Webpage Request for quotationCAS: 137-40-6
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: Sodium propionate Visit Supplier Webpage Request for quotationCAS: 137-40-6
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: Propionic acid, sodium salt Request for quotation
CAS: 137-40-6
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 137-40-6
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Multiple SpecificationsSpot supply
Product Name: Sodium propionate Visit Supplier Webpage Request for quotationCAS: 137-40-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Featured ProductsSpot supply
Product Name: SODIUM PROPIONATE Request for quotationCAS: 137-40-6
Tel: +86-518-85110306
Email: sales0257@jskolod.com
Mobile: +86-18805130257
QQ: 3287434604
Wechat: +86-18805130257
WhatsApp: +86-18805130257
Spot supply
Product Name: Propionic acid, sodium salt Request for quotationCAS: 137-40-6
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: Propionic acid, sodium salt Request for quotationCAS: 137-40-6
Tel: +86-17505207175
Email: r@reformchem.com
Mobile: +86-17505207175
QQ: 3787852685
Wechat: chemical6666
Spot supply
Product Name: Propionic acid, sodium salt Request for quotationCAS: 137-40-6
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Wechat: chemical6666
Multiple SpecificationsSpot supply
Product Name: Sodium propionate Visit Supplier Webpage Request for quotationCAS: 137-40-6
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: Sodium Propionate Visit Supplier Webpage Request for quotationCAS: 137-40-6
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: Sodium propionate Visit Supplier Webpage Request for quotationCAS: 137-40-6
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Product Name: Propionic acid, sodium salt Request for quotation
CAS: 137-40-6
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 137-40-6
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Multiple SpecificationsSpot supply
Product Name: Sodium propionate Visit Supplier Webpage Request for quotationCAS: 137-40-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
component of Prophyllin
N-[4-(2-甲氧基苯氧基)苯磺酰基]-DL-亮氨酸
Octadecanoic acid, 11-methoxy-, methyl ester
2-(2-羟基-5-叔辛基苯基)苯并三唑,也叫做紫外线吸收剂UV329
法罗培南钠水合物
2-{bicyclo[2.2.1]heptan-2-yl}-1-(4-methoxy-2-methylphenyl)ethan-1-amine
2-氨基-5-溴异烟酸乙酯
2-Butanone, 4-ethoxy-
1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE (MONOSODIUM SALT)
(1R,2R)-1-氨基-2-(二氟甲基)-N-[(1-甲基环丙基)磺酰基]环丙烷甲酰胺盐酸盐
N-[4-(2-甲氧基苯氧基)苯磺酰基]-DL-亮氨酸
Octadecanoic acid, 11-methoxy-, methyl ester
2-(2-羟基-5-叔辛基苯基)苯并三唑,也叫做紫外线吸收剂UV329
法罗培南钠水合物
2-{bicyclo[2.2.1]heptan-2-yl}-1-(4-methoxy-2-methylphenyl)ethan-1-amine
2-氨基-5-溴异烟酸乙酯
2-Butanone, 4-ethoxy-
1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE (MONOSODIUM SALT)
(1R,2R)-1-氨基-2-(二氟甲基)-N-[(1-甲基环丙基)磺酰基]环丙烷甲酰胺盐酸盐
Raw Materials for component of Prophyllin